I've been to three breweries in New York; Keuka, Horseheads, and Ithaca. Ithaca had my favorite brews, Keuka has the best tasting room, and Horseheads was small and somewhat non-descript. Still cool though. At Ithaca one beer we sampled was one that they do not serve on a large scale. It is an unfiltered version of their Apricot Wheat that they called Rough Draft. It's made with fresh apricots, rather than syrup as their regular Apricot is, and since it's unfiltered, it is a lot hazier than it's clear counterpart. We liked it so much that we bought a growler.
I've also been to two winery/breweries in the Finger Lakes; Wagner Winery/Brewery and Miles Wine Cellar. Wagner is a full scale brewery with tastings. Miles was a small operation that seemed to be pretty new to the beer game. They both have gorgeous locations on the East and West of Seneca Lake, respectively.
In general, New York has some really solid breweries. These are the other six that I have tried but haven't visited yet; Southern Tier, Saranac (Matt Brewing), Six Point, Brooklyn, Blue Point, and Brewery Ommegang.
This is a map for the places that I have visited or tried so far. Go to this page for the full list and map of the rest of New York State's breweries.
As everyone knows, there are two distinct regions of New York State; NYC and Upstate. I suggest visiting the breweries in that order, NYC first, and then go relax in Upstate.
1. Blue Point
3. Six Point
4. Brewery Ommegang
5. Matt Brewing
11. Southern Tier.
View New York Breweries in a larger map